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Methoxyflurane and Rimactane

Determining the interaction of Methoxyflurane and Rimactane and the possibility of their joint administration.

Check result:
Methoxyflurane <> Rimactane
Relevance: 12.06.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using rifAMPin together with methoxyflurane may increase the risk of side effects of methoxyflurane. Contact your doctor if you experience increased side effects. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: Coadministration with drugs that induce CYP450 isoenzymes, particularly 2E1 and/or 2A6, may increase the rate of methoxyflurane metabolism and its potential toxicity.

MANAGEMENT: Concomitant use of methoxyflurane with CYP450 2E1 and/or 2A6 inducers should generally be avoided.

References
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Methoxyflurane

Generic Name: methoxyflurane

Brand name:

Synonyms: n.a.

Rimactane

Generic Name: rifampin

Brand name: Rifadin, Rifadin IV, Rimactane

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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