Methyclothiazide and Succinylcholine Chloride
Determining the interaction of Methyclothiazide and Succinylcholine Chloride and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Before you undergo any procedure where methyclothiazide may be used, let your doctor know if you are currently using succinylcholine or other diuretics. Diuretics can cause potassium loss and prolong the effects of succinylcholine. You should be closely monitored by the doctor during the procedure, and the dosage of succinylcholine adjusted as necessary. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Diuretics may induce hypokalemia and prolong the neuromuscular blocking effects of nondepolarizing muscle relaxants.
MANAGEMENT: Close monitoring for prolonged neuromuscular blockade, potassium replacement when indicated, and neuromuscular blocker dose adjustment is recommended.
- Agencia EspaƱola de Medicamentos y Productos Sanitarios Healthcare "Centro de informaciĆ³n online de medicamentos de la AEMPS - CIMA. Available from: URL: https://cima.aemps.es/cima/publico/home.html." ([2018]):
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. HydroDIURIL (hydrochlorothiazide)." Merck & Co, Inc, West Point, PA.
- Miller RD, Roderick LL "Diuretic-induced hypokalemia, pancuronium neuromuscular blockade and its antagonism by neostigmine." Br J Anaesth 50 (1978): 541-4
Generic Name: methyclothiazide
Brand name: Aquatensen, Enduron
Synonyms: n.a.
Generic Name: succinylcholine
Brand name: Anectine, Quelicin
Synonyms: Succinylcholine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Methyclothiazide-Succinylcholine Chloride Injection
- Methyclothiazide-Suclear
- Methyclothiazide-Sucralfate
- Methyclothiazide-Sucralfate Oral Suspension
- Methyclothiazide-Sucralfate Suspension
- Methyclothiazide-Sucralfate Tablet
- Succinylcholine Chloride-Methyl Aminolevulinate
- Succinylcholine Chloride-Methyl aminolevulinate topical
- Succinylcholine Chloride-Methyl aminolevulinate Topical application
- Succinylcholine Chloride-Methyl B-12 vitamin B12
- Succinylcholine Chloride-Methyl Salicylate and Menthol Cream and Ointment
- Succinylcholine Chloride-Methyl Salicylate and Menthol Lotion