Methyldopate and Tofranil-PM
Determining the interaction of Methyldopate and Tofranil-PM and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Isolated reports have suggested that tricyclic antidepressants may decrease the antihypertensive effect of methyldopa. These reports have not been confirmed by other small studies.
- White AG "Methyldopa and amitriptyline." Lancet 2 (1965): 441
- Reid JL, Porsius AJ, Zamboulis C, Polak G, Hamilton CA, Dean CR "The effects of desmethylimipramine on the pharmacological actions of alpha methyldopa in man." Eur J Clin Pharmacol 16 (1979): 75-80
Generic Name: methyldopa
Brand name: Aldomet
Synonyms: Methyldopa
Generic Name: imipramine
Brand name: Tofranil-PM, Tofranil
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Methyldopate-Tol-Tab
- Methyldopate-Tolazamide
- Methyldopate-Tolbutamide
- Methyldopate-Tolcapone
- Methyldopate-Tolectin 600
- Methyldopate-Tolectin DS
- Tofranil-PM-Methyldopate hydrochloride
- Tofranil-PM-Methylene Blue
- Tofranil-PM-Methylene blue injection
- Tofranil-PM-Methylene blue Oral, Intravenous
- Tofranil-PM-Methylergonovine
- Tofranil-PM-Methylergonovine Injection