Metoprolol and Hydrochlorothiazide Extended-Release Tablets and Proglycem (Diazoxide Capsules)
Determining the interaction of Metoprolol and Hydrochlorothiazide Extended-Release Tablets and Proglycem (Diazoxide Capsules) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using diazoxide together with hydroCHLOROthiazide may increase your blood sugar levels and could cause your blood sugar levels to become too high. Symptoms of high blood sugar are increased thirst, increased hunger, and increased urination. You should contact your doctor if you experience loss of blood sugar control. You may need a dose adjustment or check your blood sugar more often to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: The combination of thiazide diuretics and diazoxide may result in profound and prolonged hyperglycemia. The mechanism may be related to additive hyperglycemic effects.
MANAGEMENT: Blood glucose monitoring is recommended during coadministration.
- Seltzer HS, Allen EW "Hyperglycemia and inhibition of insulin secretion during administration of diazoxide and trichlormethiazide in man." Diabetes 18 (1969): 19-28
Generic Name: hydrochlorothiazide / metoprolol
Brand name: Dutoprol, Lopressor HCT
Synonyms: Hydrochlorothiazide and metoprolol, Metoprolol and Hydrochlorothiazide
Generic Name: diazoxide
Brand name: Proglycem, Hyperstat
Synonyms: Proglycem
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Metoprolol and Hydrochlorothiazide Extended-Release Tablets-Proglycem (Diazoxide Suspension)
- Metoprolol and Hydrochlorothiazide Extended-Release Tablets-Prograf
- Metoprolol and Hydrochlorothiazide Extended-Release Tablets-Prograf (Tacrolimus Capsules)
- Metoprolol and Hydrochlorothiazide Extended-Release Tablets-Prograf (Tacrolimus Granules for Suspension)
- Metoprolol and Hydrochlorothiazide Extended-Release Tablets-Prograf (Tacrolimus Injection)
- Metoprolol and Hydrochlorothiazide Extended-Release Tablets-Prograf Intravenous
- Proglycem (Diazoxide Capsules)-Metoprolol and Hydrochlorothiazide Tablets
- Proglycem (Diazoxide Capsules)-Metoprolol Extended-Release Capsules
- Proglycem (Diazoxide Capsules)-Metoprolol Extended-Release Tablets
- Proglycem (Diazoxide Capsules)-Metoprolol Injection
- Proglycem (Diazoxide Capsules)-Metoprolol Intravenous
- Proglycem (Diazoxide Capsules)-Metoprolol Succinate