Metoprolol Tartrate and Hydrochlorothiazide and Xgeva

• Generic Name: hydrochlorothiazide / metoprolol
• Dosage Forms: tablet
• Other Brand Names: Dutoprol, Lopressor HCT

Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.

Metoprolol is a beta-blocker. Beta-blockers affect the heart and circulation (blood flow through arteries and veins).

Hydrochlorothiazide and metoprolol is a combination medicine used to treat high blood pressure (hypertension).

Hydrochlorothiazide and metoprolol may also be used for purposes not listed in this medication guide.

• Generic Name: denosumab
• Dosage Forms: injection
• Other Brand Names: Xgeva, Prolia

Xgeva (denosumab) is a monoclonal antibody. Monoclonal antibodies are made to target and destroy only certain cells in the body. This may help to protect healthy cells from damage.

The Xgeva brand of denosumab is used to prevent bone fractures and other skeletal conditions in people with multiple myeloma, and in people with tumors that have spread to the bone.

Xgeva is also used to treat giant cell bone tumor in adults and teenagers with fully matured bone structure.

Xgeva is also used to treat high blood levels of calcium caused by cancer, when other medicines such as pamidronate or zoledronic acid (Zometa) have been used without success.

Prolia is another brand of denosumab used to treat osteoporosis in postmenopausal women who have high risk of bone fracture.