Metreleptin Subcutaneous and Yuvafem local

• Generic Name: metreleptin
• Dosage Forms: n.a.
• Other Brand Names: Myalept

Metreleptin injection is used together with a proper diet as replacement therapy to treat problems caused by leptin deficiency in patients with congenital or acquired generalized lipodystrophy.

Metreleptin is only available under a restricted distribution program called Myalept™ REMS program.

• Generic Name: estradiol topical
• Dosage Forms: vaginal tablet
• Other Brand Names: Estrace Vaginal, Estring, Vagifem, Yuvafem, Imvexxy

Estradiol is a form of estrogen, a female sex hormone that regulates many processes in the body.

Some estradiol products placed directly into the vagina are used for "local" treatment of vaginal menopause symptoms (such as dryness, burning, and irritation). Other vaginal estradiol products are used for treating vaginal menopause symptoms and symptoms that affect other parts of the body (such as hot flashes). This type of vaginal estradiol has "systemic" effects, meaning that it can affect parts of the body other than where the medicine is directly applied.

This medication guide provides information about Yuvafem for local treatment of vaginal symptoms of menopause (such as dryness, itching, irritation, and pain during sexual intercourse).

Yuvafem (local) may also be used for purposes not listed in this medication guide.