Metronidazole Intravenous and Quinidex Extentabs

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

The combination of ciprofloxacin and metronidazole has been reported to increase the serum concentration of quinidine in a patient treated for atrial fibrillation and suspected diverticulitis. The patient's trough serum quinidine level was 6.3 mcg/mL during coadministration with the antibiotics and declined to 2.3 mcg/mL 3 days after completion of the antibiotics. No clinically significant adverse effects were observed. The exact mechanism of interaction is unknown. Neither metronidazole nor ciprofloxacin are known to significantly inhibit CYP450 3A4, the isoenzyme responsible for the metabolism of quinidine. Moreover, ciprofloxacin (750 mg orally every 12 hours for 5 days) was found to have no significant effect on the pharmacokinetics or pharmacologic effects of quinidine (400 mg single oral dose) in a study of seven healthy volunteers.

Metronidazole Intravenous

Generic Name: metronidazole

Brand name: Flagyl, MetroGel, FIRST Metronidazole, Flagyl 375

Synonyms: Metronidazole, MetroNIDAZOLE (Systemic)

What is Metronidazole Intravenous?

Quinidex Extentabs

Generic Name: quinidine

Brand name: Quin-G, Cardioquin, Quinora, Quinidex Extentabs, Quinaglute Dura-Tabs, Quin-Release

Synonyms: n.a.

What is Quinidex Extentabs?