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MG Plus Protein and NegGram

Determining the interaction of MG Plus Protein and NegGram and the possibility of their joint administration.

Check result:
MG Plus Protein <> NegGram
Relevance: 28.02.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Nalidixic acid and magnesium amino acids chelate should not be taken orally at the same time. Products that contain magnesium, aluminum, calcium, iron, and/or other minerals may interfere with the absorption of nalidixic acid into the bloodstream and reduce its effectiveness. If possible, it may be best to avoid taking magnesium amino acids chelate while your are being treated with nalidixic acid. Otherwise, you should take nalidixic acid either 2 hours before or 2 hours after the magnesium amino acids chelate dose. Talk to a healthcare professional if you are not sure whether a product contains something that could potentially interact with your medication or if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

ADJUST DOSING INTERVAL: Oral preparations that contain magnesium, aluminum, or calcium may significantly decrease the gastrointestinal absorption of nalidixic acid. Absorption may also be reduced by sucralfate, which contains aluminum, as well as other polyvalent cations such as iron and zinc. The mechanism is chelation of nalidixic acid by polyvalent cations, forming a complex that is poorly absorbed from the gastrointestinal tract.

MANAGEMENT: When coadministration cannot be avoided, nalidixic acid should be dosed at least 2 hours before or 2 hours after polyvalent cation-containing products to minimize the potential for interaction.

References
  • "Product Information. NegGram (nalidixic acid)." Sanofi Winthrop Pharmaceuticals, New York, NY.
MG Plus Protein

Generic Name: magnesium amino acids chelate

Brand name: Balnetar, Denorex Extra Strength, DHS Tar Shampoo, Elta Tar, Ionil T, MG217 Medicated Tar, Neutrogena T/Gel, Oxipor VHC, Psoriasin, Scytera, Tarsum, Tegrin Medicated, Theraplex T, Coal Tar, Zetar, G-TAR, Zeprime Tar Emulsion, Ionil T Plus, Pentrax, Denorex, Estar, Betatar Gel, Fototar, Doak Tar, Therapeutic, Neutrogena T/Gel Extra Strength, Denorex Medicated Shampoo and Conditioner, Denorex Dry Scalp, MG217 Psoriasis, Doak Tar Oil, Neutrogena T/Derm, Pentrax Gold, T/Gel Conditioner, Tegrin Medicated Soap, Psorigel, Polytar, Doctar, Cutar, Reme-T, Tera Gel, Exorex, Polytar Mild, Psoriderm, Clinitar, Alphosyl, Alphosyl 2 in 1, Carbo-Dome, Coal Tar Strong, T/Gel, Doak Oil Forte, Amcal Anti Itch Bath Solution, Hamilton Formicare Skin Wash, Apha Keri Tar, Neutrogena T-Gel Conditioner, Orion Coal Tar, Linotar, Exorex Penetrating Emulsion Psoriasis Medication, Apha Keri Tar Gel, Linotar Gel 2, Linotar Gel 3, Hamilton Pine Tar with Menthol, Eczema Cream, Pinetarsol Tar, Resolve Itch Cleansing Gel, PC Tar, Anti-Dandruff, Psoriasin Advanced Treatment, Psoriatar, Chelated Magnesium, MG Plus Protein

Synonyms: n.a.

NegGram

Generic Name: nalidixic acid

Brand name:

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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Disease interaction