Midazolam Hydrochloride and Stalevo
Determining the interaction of Midazolam Hydrochloride and Stalevo and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Midazolam can decrease the effects of levodopa in some people. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your Parkinson symptoms worsen. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Benzodiazepines may decrease the therapeutic effects of levodopa in patients with Parkinson's disease. The mechanism is unknown.
MANAGEMENT: Patients receiving this combination should be monitored for altered clinical response. The benzodiazepine should be discontinued if an interaction is suspected.
- Hunter KR, Stern GM, Laurence DR "Use of levodopa with other drugs." Lancet 2 (1970): 1283-5
- Yosselson-Superstine S, Lipman AG "Chlordiazepoxide interaction with levodopa." Ann Intern Med 96 (1982): 259-60
- Mackie L "Drug antagonism." Br Med J 2 (1971): 651
Generic Name: midazolam
Brand name: Versed, Nayzilam
Synonyms: Midazolam
Generic Name: carbidopa / entacapone / levodopa
Brand name: Stalevo, Stalevo 100, Stalevo 125, Stalevo 150, Stalevo 200, Stalevo 50, Stalevo 75
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Midazolam Hydrochloride-Stalevo 100
- Midazolam Hydrochloride-Stalevo 125
- Midazolam Hydrochloride-Stalevo 150
- Midazolam Hydrochloride-Stalevo 200
- Midazolam Hydrochloride-Stalevo 50
- Midazolam Hydrochloride-Stalevo 75
- Stalevo-Midazolam injection
- Stalevo-Midazolam Injection Hospira
- Stalevo-Midazolam nasal
- Stalevo-Midazolam Nasal Spray
- Stalevo-Midazolam Syrup
- Stalevo-Midodrine