Midazolam Injection Hospira and Sustiva

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using midazolam and efavirenz is not recommended. Taking these drugs together can cause symptoms of prlonged drowsiness, dizziness, confusion, or weak or shallow breathing. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

CONTRAINDICATED: Efavirenz may interfere with the metabolism of benzodiazepines. The mechanism is competitive inhibition of the CYP450 3A4 enzyme. The accumulation of benzodiazepines, especially midazolam and triazolam is associated with potentially serious and/or life-threatening events (e.g., prolonged sedation, respiratory depression).

MANAGEMENT: Midazolam or triazolam should not be administered concurrently with efavirenz.

Midazolam Injection Hospira

Generic Name: midazolam

Brand name: Versed, Nayzilam

Synonyms: Midazolam

What is Midazolam Injection Hospira?

Sustiva

Generic Name: efavirenz

Brand name: Sustiva

Synonyms: n.a.

What is Sustiva?