Mifepristone Tablets and Pramipexole ER Tablets

• Generic Name: mifepristone
• Dosage Forms: tablet
• Other Brand Names: Korlym, Mifeprex

This medication guide provides information about the Korlym brand of mifepristone. Mifeprex is another brand of mifepristone that is not covered in this medication guide.

Korlym is used to treat high blood sugar (hyperglycemia) in adults with Cushing's syndrome who also have type 2 diabetes mellitus or glucose intolerance.

Korlym should not be used to treat type 2 diabetes that is not related to Cushing's syndrome.

Korlym may also be used for purposes not listed in this medication guide.

• Generic Name: pramipexole
• Dosage Forms: tablet, extended release
• Other Brand Names: Mirapex, Mirapex ER

Symptomatic management of idiopathic parkinsonian syndrome.

Used as an adjunct to levodopa for the symptomatic management of parkinsonian syndrome in patients with advanced disease.

Also used as monotherapy for the initial symptomatic management of parkinsonian syndrome. Most clinicians would use levodopa for initial therapy in individuals >70 years of age (less likely than younger individuals to develop levodopa-related motor complications and because of concerns about cognitive dysfunction), in patients with cognitive impairment, and in those with severe disease. A dopamine receptor agonist may be preferred for initial therapy in patients ≤70 years of age.

Symptomatic management of moderate-to-severe primary restless legs syndrome (Ekbom syndrome).