About us Contacts Drug interactions: 390 212
Drug search by name

Mifepristone Tablets (For Ending Early Pregnancy) and Xarelto Starter Pack

Determining the interaction of Mifepristone Tablets (For Ending Early Pregnancy) and Xarelto Starter Pack and the possibility of their joint administration.

Check result:
Mifepristone Tablets (For Ending Early Pregnancy) <> Xarelto Starter Pack
Relevance: 26.09.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using miFEPRIStone together with rivaroxaban may increase the risk and/or severity of vaginal bleeding in women. Prolonged, heavy bleeding may require emergency medical treatment. Talk to your doctor if you have any questions or concerns. Your doctor may already be aware of the risks, but has determined that this is the best course of treatment for you and has taken appropriate precautions and is monitoring you closely for any potential complications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

CONTRAINDICATED: Concomitant use of anticoagulants may exacerbate mifepristone-induced vaginal bleeding in women. Prolonged, potentially heavy bleeding lasting approximately 9 to 30 days typically follows mifepristone use in termination of pregnancy. Because it is a progesterone receptor antagonist, mifepristone can also promote unopposed endometrial proliferation that may result in endometrium thickening, cystic dilatation of endometrial glands, and vaginal bleeding when used daily to control hyperglycemia secondary to hypercortisolism in patients with endogenous Cushing's syndrome.

MANAGEMENT: Concurrent anticoagulant therapy is considered a contraindication in the use of mifepristone for pregnancy termination. When used daily to control hyperglycemia secondary to hypercortisolism in patients with endogenous Cushing's syndrome, mifepristone treatment should be administered cautiously in women who are receiving anticoagulant therapy. Patients who experience vaginal bleeding should be referred to a gynecologist for further evaluation.

References
  • "Product Information. Mifeprex (mifepristone)" Danco Laboratories, New York, NY.
  • "Product Information. Korlym (mifepristone)." Corcept Therapeutics Incorporated, Menlo Park, CA.
Mifepristone Tablets (For Ending Early Pregnancy)

Generic Name: mifepristone

Brand name: Korlym, Mifeprex

Synonyms: Mifepristone

Xarelto Starter Pack

Generic Name: rivaroxaban

Brand name: Xarelto, Xarelto Starter Pack

Synonyms: Xarelto

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.