Migalastat Hydrochloride and Stiolto Respimat

• Generic Name: migalastat
• Dosage Forms: n.a.
• Other Brand Names: Galafold

Migalastat hydrochloride is an alpha-galactosidase A (alpha-Gal A) pharmacological chaperone indicated for the treatment of adults with a confirmed diagnosis of Fabry disease and an amenable galactosidase alpha gene (GLA) variant based on in vitro assay data.

This indication is approved under accelerated approval based on reduction in kidney interstitial capillary cell globotriaosylceramide (KIC GL-3) substrate. Continued approval for this indication may be contingent upon verification and description of clinical benefit in confirmatory trials.

• Generic Name: olodaterol / tiotropium
• Dosage Forms: spray, metered
• Other Brand Names: Stiolto Respimat, Stiolto Respimat 28 ACT, Stiolto Respimat 60 ACT, Stiolto Respimat 10 ACT

Stiolto Respima containes a combination of olodaterol and tiotropium. Olodaterol is a long-acting bronchodilator. Tiotropium is an anticholinergic. These medications work by relaxing muscles in the airways to improve breathing.

Stiolto Respimat is used to prevent airflow obstruction and reduce flare-ups in adults with COPD (chronic obstructive pulmonary disease), including bronchitis and emphysema.

Stiolto Respimat will not treat a bronchospasm attack that has already begun.

Stiolto Respimat is for use only in people with COPD and should not be used to treat asthma.