Milnacipran Hydrochloride and Naloxegol Oxalate

• Generic Name: milnacipran
• Dosage Forms: n.a.
• Other Brand Names: Savella, Savella Titration Pack

Management of fibromyalgia.

Has been used in the treatment of major depressive disorder and is approved for treating depression in some countries; this indication is not an FDA-labeled use.

Insufficient data, to date, to determine if efficacy and tolerability of milnacipran as an antidepressant are superior, inferior, or equal to that of other antidepressants for acute treatment of major depressive disorder. Some studies indicate improved tolerability with milnacipran when compared with tricyclic antidepressants.

• Generic Name: naloxegol
• Dosage Forms: n.a.
• Other Brand Names: Movantik

Management of opiate-induced constipation in patients with chronic non-cancer-related pain, including those with chronic pain related to prior cancer or its treatment who do not require frequent (e.g., weekly) increases in opiate dosage.