Minivelle Transdermal and Probuphine

• Generic Name: estradiol
• Dosage Forms: transdermal film, extended release
• Other Brand Names: Alora, Climara, Estradiol Patch, Menostar, Minivelle, Vivelle-Dot, Estraderm, Vivelle, Delestrogen, Depo-Estradiol, Divigel, Elestrin Pump, Estrasorb, EstroGel Pump, Evamist, Estrace, DepoEstradiol, Elestrin, Estradot, Estrogel, Femtrace, Femring, Gynodiol

Estradiol transdermal gel, patch, and spray are used to treat moderate to severe hot flashes and other symptoms of menopause or low amounts of estrogen. It is also used to treat changes in and around the vagina (such as vaginal dryness, itching, and burning) caused by low estrogen levels or menopause. This medicine is also used to treat certain conditions in women before menopause if their ovaries do not make enough estrogens naturally, and prevent osteoporosis after menopause.

Estradiol is an estrogen hormone. The hormone from the patch, gel, and spray is absorbed through your skin into your body. It works by preventing symptoms, such as feelings of warmth in the face, neck, and chest, or sudden strong feelings of heat and sweating (hot flashes) in women during menopause.

This medicine is available only with your doctor's prescription.

• Generic Name: buprenorphine
• Dosage Forms: implant
• Other Brand Names: Probuphine, Belbuca, Buprenex, Butrans, Sublocade, Subutex

Probuphine (buprenorphine) is an opioid medication. An opioid is sometimes called a narcotic.

Probuphine implants are used to treat narcotic addiction in certain people whose addiction has already been treated and controlled with other forms of buprenorphine (such as Subutex or Suboxone). Probuphine implants are for adults and teenagers who are at least 16 years old.

Probuphine implants are available only from a certified pharmacy under a special program. You must be registered in the program and understand the risks and benefits of using this medicine. The implants are not for use as a pain medication.