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Mintox Plus and Orphacol

Determining the interaction of Mintox Plus and Orphacol and the possibility of their joint administration.

Check result:

Mintox Plus <> Orphacol

Relevance: 27.08.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Aluminum hydroxide may interfere with the absorption of cholic acid and reduce its effectiveness in treating your condition. You should take cholic acid at least 1 hour before or 4 to 6 hours (or at as great an interval as possible) after aluminum hydroxide. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medication without first talking to your doctor.

Professional:

ADJUST DOSING INTERVAL: Bile acid binding resins can adsorb bile acids and may reduce the bioavailability of cholic acid. Aluminum-based antacids have been shown to adsorb bile acids in vitro and may interact similarly.

MANAGEMENT: Cholic acid should be taken at least 1 hour before or 4 to 6 hours (or at as great an interval as possible) after a bile acid binding resin or aluminum-based antacid.

References

"Product Information. Cholbam (cholic acid)." Manchester Pharmaceutical, Fort Collins, CO.

Mintox Plus

Generic Name: aluminum hydroxide / magnesium hydroxide / simethicone

Brand name: Gelusil, Mintox Plus, Almacone, Mag-al Plus, Mi-Acid, Milantex, Mintox, Mylanta Maximum Strength, Rulox, Mylanta Fast Acting, Mylanta DS Fast Acting, Maalox Plus, Masanti DS, Masanti II, Masanti, Alamag Plus, Mi-Acid II, Almacone-2, Mylagen, Mylagen-II, Magaant, Ri-Mox Plus, Rulox Plus, Di-Gel, Ri-Gel II, Uni-Lan, Uni-Lan II, Urban, Urban DS, Maldroxal Plus, Maalox Plus Extra Strength, Tempo, Mylanta, Maalox Max, Maalox, Aldroxicon I, Aldroxicon II, Maalox Antacid Antigas Regular Strength, Mintox Extra Strength, Mintox Maximum Strength, Comfort Gel Original, Comfort Gel Extra Strength, Mylanta Maximum Strength Cherry, Maalox Max Wild Berry, Maalox Advanced Maximum Strength, Milantex Maximum Strength, Maalox Advanced Regular Strength, Geri-Lanta, Mag-al Plus XS, Mylanta Maximum Strength Vanilla Caramel, Mi-Acid Maximum Strength, Di-Gel Liquid

Synonyms: n.a.

What is Mintox Plus?

Orphacol

Generic Name: cholic acid

Brand name: Cholbam

Synonyms: Cholic acid, Cholic Acid

What is Orphacol?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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