Miostat and Rocuronium Bromide Injection

• Generic Name: carbachol ophthalmic
• Dosage Forms: intraocular solution
• Other Brand Names: Isopto Carbachol, Miostat, Carboptic, Carbastat

Carbachol lowers pressure in the eye by increasing the amount of fluid that drains from the eye.

Miostat (for the eye) is used to reduce pressure inside the eye after cataract surgery.

Miostat may also be used for purposes not listed in this medication guide.

• Generic Name: rocuronium
• Dosage Forms: injection
• Other Brand Names: Zemuron

Production of skeletal muscle relaxation during surgery after general anesthesia has been induced.

Facilitation of endotracheal intubation (rapid sequence and routine tracheal intubation).

Also has been used to facilitate mechanical ventilation in the ICU; however, manufacturer states that prolonged use in this setting has not been evaluated. Whenever neuromuscular blocking agents are used in the ICU, consider benefits versus risks of such therapy and assess patients frequently to determine need for continued paralysis. (See Intensive Care Setting under Cautions.)

Compared with other neuromuscular blocking agents, rocuronium has a rapid onset and intermediate duration of action. Recommended as an alternative to succinylcholine for rapid sequence intubation. When given in sufficient doses (e.g., ≥1 mg/kg), produces similar intubating conditions to succinylcholine.