Mipomersen Sodium and Orphenadrine Injection

• Generic Name: mipomersen
• Dosage Forms: n.a.
• Other Brand Names: Kynamro

Adjunct to other antilipemic agents and diet to reduce LDL-cholesterol, apolipoprotein B (apo B), total cholesterol, and non-HDL-cholesterol concentrations in the management of homozygous familial hypercholesterolemia (designated an orphan drug by US FDA for use in this condition).

Safety and efficacy not established in patients with hypercholesterolemia who do not have homozygous familial hypercholesterolemia.

Safety and efficacy as an adjunct to LDL apheresis not established; use in combination with LDL apheresis not recommended.

Effects on cardiovascular morbidity and mortality not established.

• Generic Name: orphenadrine
• Dosage Forms: n.a.
• Other Brand Names: Norflex, Banflex, Orphenate, Flexoject, Flexon, Mio-Rel, Myolin, Orfro, Norflex Injectable, Antiflex

• It is used to relax muscles.