Mipomersen Sodium and Tolinase

• Generic Name: mipomersen
• Dosage Forms: n.a.
• Other Brand Names: Kynamro

Adjunct to other antilipemic agents and diet to reduce LDL-cholesterol, apolipoprotein B (apo B), total cholesterol, and non-HDL-cholesterol concentrations in the management of homozygous familial hypercholesterolemia (designated an orphan drug by US FDA for use in this condition).

Safety and efficacy not established in patients with hypercholesterolemia who do not have homozygous familial hypercholesterolemia.

Safety and efficacy as an adjunct to LDL apheresis not established; use in combination with LDL apheresis not recommended.

Effects on cardiovascular morbidity and mortality not established.

• Generic Name: tolazamide
• Dosage Forms: Tablets, USP
• Other Brand Names: Tolinase

Tolazamide is used to treat high blood sugar levels caused by a type of diabetes mellitus (sugar diabetes) called type 2 diabetes. In type 2 diabetes, your body does not work properly to store excess sugar and the sugar remains in your bloodstream. Chronic high blood sugar can lead to serious health problems in the future .

Proper diet is the first step in managing type 2 diabetes, but often medicines are needed to help your body. Tolazamide belongs to a class of drugs called sulfonylureas. It causes your pancreas to release more insulin into the blood stream .

This medicine is available only with your doctor's prescription .