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Mirabegron and Nutropin AQ NuSpin 10

Determining the interaction of Mirabegron and Nutropin AQ NuSpin 10 and the possibility of their joint administration.

Check result:

Mirabegron <> Nutropin AQ NuSpin 10

Relevance: 12.10.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Coadministration with inducers of CYP450 3A4 and/or P-glycoprotein may decrease the plasma concentrations of mirabegron, which has been shown in vitro to be a substrate of the isoenzyme and efflux transporter. However, in vivo results indicate that these pathways may play a limited role in the overall elimination. In healthy study subjects, mirabegron peak plasma concentration (Cmax) and systemic exposure (AUC) decreased by less than 50% when a single 100 mg dose of mirabegron was administered following multiple dosing of rifampin 600 mg once daily. No dosage adjustment is recommended when mirabegron is administered in combination with rifampin and probably other CYP450 3A4/P-gp inducers.

References

"Product Information. Myrbetriq (mirabegron)." Astellas Pharma US, Inc, Deerfield, IL.

Mirabegron

Generic Name: mirabegron

Brand name: Myrbetriq

Synonyms: n.a.

What is Mirabegron?

Nutropin AQ NuSpin 10

Generic Name: somatropin

Brand name: Genotropin, Humatrope, Norditropin FlexPro Pen, Nutropin AQ NuSpin 10, Nutropin AQ Pen 10 Cartridge, Omnitrope, Saizen, Serostim, Zomacton, Zorbtive, Genotropin Miniquick, Norditropin Nordiflex Pen, Tev-Tropin, Nutropin, Norditropin, Nutropin AQ, Nutropin Depot, Norditropin Cartridge, Saizen Click-Easy, Omnitrope Pen 5 Cartridge, HumatroPen, Omnitrope Pen 10 Cartridge, Nutropin AQ Pen 20 Cartridge, Nutropin AQ NuSpin 5, Nutropin AQ NuSpin 20, Saizen Kit

Synonyms: Nutropin AQ

What is Nutropin AQ NuSpin 10?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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