Mirapex ER and Sandimmune

• Generic Name: pramipexole
• Dosage Forms: tablet, extended release
• Other Brand Names: Mirapex, Mirapex ER

Mirapex ER has some of the same effects as a chemical called dopamine, which occurs naturally in your body. Low levels of dopamine in the brain are associated with Parkinson's disease.

Mirapex ER is used to treat symptoms of Parkinson's disease (stiffness, tremors, muscle spasms, and poor muscle control). This medicine is also used to treat restless legs syndrome (RLS).

Only immediate-release Mirapex ER (Mirapex) is approved to treat either Parkinson symptoms or RLS. Extended-release this medicine (Mirapex ER) is approved only to treat Parkinson symptoms.

Parkinson's and RLS are two separate disorders. Having one of these conditions will not cause you to have the other condition.

Mirapex ER may also be used for purposes not listed in this medication guide.

• Generic Name: cyclosporine
• Dosage Forms: capsule, injection, oral solution
• Other Brand Names: Sandimmune, Gengraf, Neoral, Sandimmune

Cyclosporine injection is given together with a steroid medicine to prevent the body from rejecting a transplanted organ (e.g., kidney, liver, or heart). It belongs to a group of medicines known as immunosuppressive agents.

When a patient receives an organ transplant, the body's white blood cells will try to get rid of (reject) the transplanted organ. Cyclosporine works by suppressing the immune system to prevent the white blood cells from trying to get rid of the transplanted organ.

Cyclosporine is a very strong medicine. It can cause side effects that can be very serious, such as high blood pressure, kidney problems, or liver problems. It may also decrease the body's ability to fight infections. You and your doctor should talk about the benefits this medicine will do as well as the risks of using it.

This medicine is to be given only by or under the direct supervision of a doctor.