Mitotane and Phenobarbital Sodium Injection
Determining the interaction of Mitotane and Phenobarbital Sodium Injection and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Mitotane could theoretically decrease the plasma levels and clinical effectiveness of barbiturates by inducing their hepatic metabolism. Until more data are available, be cognizant of the possibility of decreased clinical effectiveness from barbiturates when mitotane is added to a patient's regimen, as well as the risk of barbiturate toxicity upon mitotane withdrawal.
- "Product Information. Lysodren (mitotane)." Bristol-Myers Squibb, Princeton, NJ.
Generic Name: phenobarbital
Brand name: Solfoton, Luminal
Synonyms: Phenobarbital, PHENobarbital
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Mitotane-Phenobarbital Tablets
- Mitotane-Phenobarbital with Belladonna Alkaloids Elixir
- Mitotane-Phenohytro
- Mitotane-Phenohytro Elixir
- Mitotane-Phenoxybenzamine
- Mitotane-Phenoxybenzamine Capsules
- Phenobarbital Sodium Injection-Mitoxantrone
- Phenobarbital Sodium Injection-Mitoxantrone Hydrochloride
- Phenobarbital Sodium Injection-Mitoxantrone Injection Concentrate
- Phenobarbital Sodium Injection-Mitoxantrone Intravenous, Injection
- Phenobarbital Sodium Injection-Mitrazol
- Phenobarbital Sodium Injection-Mitrazol Topical