Mitotane and Seconal Sodium

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Mitotane could theoretically decrease the plasma levels and clinical effectiveness of barbiturates by inducing their hepatic metabolism. Until more data are available, be cognizant of the possibility of decreased clinical effectiveness from barbiturates when mitotane is added to a patient's regimen, as well as the risk of barbiturate toxicity upon mitotane withdrawal.

Mitotane

Generic Name: mitotane

Brand name: Lysodren

Synonyms: n.a.

What is Mitotane?

Seconal Sodium

Generic Name: secobarbital

Brand name: Seconal Sodium, Seconal

Synonyms: n.a.

What is Seconal Sodium?