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Mivacron and Sufentanil Citrate

Determining the interaction of Mivacron and Sufentanil Citrate and the possibility of their joint administration.

Check result:
Mivacron <> Sufentanil Citrate
Relevance: 05.09.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Sufentanil, when combined with neuromuscular blocking agents during surgical procedures, may adversely effect cardiovascular function. Tachycardia, bradycardia, and/or hypotension may result. However, muscle relaxants and sufentanil frequently are used together during surgery. Patients should be closely monitored for clinically significant alterations in hemodynamics.

References
  • Clotz MA, Nahata MC "Clinical uses of fentanyl, sufentanil, and alfentanil." Clin Pharm 10 (1991): 581-93
  • Thomson IR, MacAdams CL, Hudson RJ, Rosenbloom M "Drug interactions with sufentanil: hemodynamic effects of premedication and muscle relaxants." Anesthesiology 76 (1992): 922-9
  • "Product Information. Sufenta (sufentanil)." Janssen Pharmaceutica, Titusville, NJ.
Mivacron

Generic Name: mivacurium

Brand name: Mivacron

Synonyms: n.a.

Sufentanil Citrate

Generic Name: sufentanil

Brand name: Dsuvia

Synonyms: Sufentanil Sublingual Tablets, SUFentanil

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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