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Mobic and Sulfamethoxazole and Trimethoprim Tablets

Determining the interaction of Mobic and Sulfamethoxazole and Trimethoprim Tablets and the possibility of their joint administration.

Check result:
Mobic <> Sulfamethoxazole and Trimethoprim Tablets
Relevance: 15.11.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Sulfamethoxazole may increase the blood levels and effects of meloxicam. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Coadministration with inhibitors of CYP450 2C9 may increase the plasma concentration of meloxicam, which is a substrate of the isoenzyme.

MANAGEMENT: The potential for an interaction should be considered during concomitant use. It is recommended to monitor patients for NSAID-related side effects and toxicity. Dose adjustment of meloxicam may be warranted.

References
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  • Cerner Multum, Inc. "Australian Product Information." O 0
Mobic

Generic Name: meloxicam

Brand name: Mobic, Vivlodex, Meloxicam Comfort Pac [DSC], Qmiiz ODT

Synonyms: n.a.

Sulfamethoxazole and Trimethoprim Tablets

Generic Name: sulfamethoxazole / trimethoprim

Brand name: Bactrim, Bactrim DS, Bactrim IV, Septra IV, SMZ-TMP DS, Sulfatrim Pediatric, Septra, Sulfatrim, Bethaprim, Cotrim, Uroplus, Uroplus DS, Cotrim DS, Bactrim Pediatric, Bethaprim Pediatric, Sulfatrim Suspension, Cotrim Pediatric, Septra DS

Synonyms: Sulfamethoxazole and trimethoprim, Sulfamethoxazole and Trimethoprim

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.