Morphine ER and Yohimbe
Determining the interaction of Morphine ER and Yohimbe and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:A double-blind, placebo-controlled study of patients with postoperative dental pain found that while yohimbine itself did not affect pain, the overall analgesic effect of morphine was significantly enhanced in the presence of yohimbine. The mechanism of interaction is unknown. Additional research involving other pain states is needed.
- Gear RW, Gordon NC, Heller PH, Levine JD "Enhancement of morphine analgesia by the alpha(2)-adrenergic antagonist yohimbine." Neuroscience 66 (1995): 5-8
Generic Name: morphine
Brand name: Arymo ER, Kadian, MorphaBond ER, MS Contin, Avinza, Duramorph PF, Infumorph, Mitigo, RMS, Roxanol
Synonyms: Morphine, Morphine (Systemic)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Morphine ER-Yohimbine
- Morphine ER-Yondelis
- Morphine ER-Yonsa
- Morphine ER-Yosprala
- Morphine ER-Yupelri
- Morphine ER-Yutiq
- Yohimbe-Morphine Extended-Release Capsules
- Yohimbe-Morphine Immediate-Release Tablets and Capsules
- Yohimbe-Morphine injection
- Yohimbe-Morphine Injection PF
- Yohimbe-Morphine Long-Acting Tablets
- Yohimbe-Morphine Oral Concentrate (20 mg/mL)