MST and Omeprazole and Sodium Bicarbonate Powder Packets
Determining the interaction of MST and Omeprazole and Sodium Bicarbonate Powder Packets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using sodium bicarbonate together with magnesium salicylate may decrease the effects of magnesium salicylate. Contact your doctor if your condition changes. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Agents that cause urinary alkalinization can reduce serum salicylate concentrations in patients receiving anti-inflammatory dosages of aspirin or other salicylates. The mechanism involves reduction in salicylate renal tubular reabsorption due to increased urinary pH, resulting in increased renal salicylate clearance especially above urine pH of 7. This interaction is sometimes exploited in the treatment of salicylate toxicity.
MANAGEMENT: Patients treated chronically with urinary alkalinizers and large doses of salicylates (i.e. 3 g/day or more) should be monitored for potentially diminished or inadequate analgesic and anti-inflammatory effects, and the salicylate dosage adjusted if necessary.
- Balali-Mood M, Prescott LF "Failure of alkaline diuresis to enhance diflunisal elimination." Br J Clin Pharmacol 10 (1980): 163-5
- Berg KJ "Acute effects of acetylsalicylic acid in patients with chronic renal insufficiency." Eur J Clin Pharmacol 11 (1977): 111-6
- Berg KJ "Acute acetylsalicylic acid poisoning: treatment with forced alkaline diuresis and diuretics." Eur J Clin Pharmacol 12 (1977): 111-6
- Brouwers JRBJ, Desmet PAGM "Pharmacokinetic-pharmacodynamic drug interactions with nonsteroidal anti-inflammatory drugs." Clin Pharmacokinet 27 (1994): 462-85
- Prescott LF, Balali-Mood M, Critchley JA, Johnstone AF, Proudfoot AT "Diuresis or urinary alkalinisation for salicylate poisoning?" Br Med J (Clin Res Ed) 285 (1982): 1383-6
Generic Name: magnesium salicylate
Brand name: Doans Pills Extra Strength, MST, Nuprin Backache, Magan, Mobidin, Doans Pills, Bayer Select Backache Pain Formula, Doans Extra Strength
Synonyms: n.a.
Generic Name: omeprazole / sodium bicarbonate
Brand name: Zegerid, Zegerid OTC
Synonyms: Omeprazole and sodium bicarbonate, Omeprazole and Sodium Bicarbonate
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- MST-Omeprazole Delayed-Release Capsules
- MST-Omeprazole Delayed-Release Capsules and Tablets (OTC)
- MST-Omeprazole Orally-Disintegrating Tablets
- MST-Omeprazole Powder for Oral Suspension
- MST-Omeprazole Tablets
- MST-Omeprazole, Clarithromycin, and Amoxicillin
- Omeprazole and Sodium Bicarbonate Powder Packets-MTX Support
- Omeprazole and Sodium Bicarbonate Powder Packets-MucaphEd
- Omeprazole and Sodium Bicarbonate Powder Packets-Mucinex Allergy
- Omeprazole and Sodium Bicarbonate Powder Packets-Mucinex Cough Mini-Melts
- Omeprazole and Sodium Bicarbonate Powder Packets-Mucinex D
- Omeprazole and Sodium Bicarbonate Powder Packets-Mucinex D Max Strength