Mycophenolic Acid Tablets and Nitrofurantoin Macrocrystals
Determining the interaction of Mycophenolic Acid Tablets and Nitrofurantoin Macrocrystals and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Nitrofurantoin may reduce the blood levels and effects of mycophenolic acid. You may need a dose adjustment if you have been taking mycophenolic acid and are starting treatment with nitrofurantoin. Contact your doctor if your symptoms worsen or your condition changes during treatment with these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Theoretically, drugs that alter the gastrointestinal flora (e.g., antibiotics) may reduce the oral bioavailability of mycophenolic acid products. Some investigators believe that antimicrobials may interfere with the enterohepatic recirculation of mycophenolic acid by decreasing bacterial hydrolytic enzymes in the gastrointestinal tract that are responsible for regenerating mycophenolic acid from its glucuronide metabolite following first-pass metabolism.
MANAGEMENT: Close clinical and laboratory monitoring for evidence of diminished immunosuppressive effect of mycophenolic acid is recommended during concomitant therapy with anti-infective agents.
- "Product Information. Myfortic (mycophenolic acid)." Novartis Pharmaceuticals, East Hanover, NJ.
- "Product Information. CellCept (mycophenolate mofetil)." Roche Laboratories, Nutley, NJ.
Generic Name: mycophenolic acid
Brand name: Myfortic
Synonyms: Mycophenolic acid, Mycophenolate Tablets Delayed Release
Generic Name: nitrofurantoin
Brand name: Furadantin, Macrobid, Macrodantin, Nitro Macro
Synonyms: Nitrofurantoin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Mycophenolic Acid Tablets-Nitrofurantoin Oral Suspension
- Mycophenolic Acid Tablets-Nitroglycerin
- Mycophenolic Acid Tablets-Nitroglycerin Controlled-Release Capsules
- Mycophenolic Acid Tablets-Nitroglycerin Dextrose
- Mycophenolic Acid Tablets-Nitroglycerin ER
- Mycophenolic Acid Tablets-Nitroglycerin in Dextrose
- Nitrofurantoin Macrocrystals-Mycostatin (Nystatin Oral Suspension)
- Nitrofurantoin Macrocrystals-Mycostatin (Nystatin Tablets and Capsules)
- Nitrofurantoin Macrocrystals-Mycostatin Suspension
- Nitrofurantoin Macrocrystals-Mydayis
- Nitrofurantoin Macrocrystals-Mydayis ER Capsules
- Nitrofurantoin Macrocrystals-Mydfrin