Naloxone Injection and Roxybond (Oxycodone Capsules and Tablets)
Determining the interaction of Naloxone Injection and Roxybond (Oxycodone Capsules and Tablets) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:The following interaction applies only if you are using naloxone in an injectable formulation: naloxone can reverse the effects of oxyCODONE. If you are a physically dependent patient you may experience withdrawal symptoms. This can cause nausea, vomiting, diarrhea, aches, fever, runny nose, sneezing, nervousness, irritability, shivering, and abdominal cramps. Talk to your doctor if you have any questions or concerns. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: This warning does not apply to the naloxone component in non-injectable formulations of naloxone-containing combination medicines. Naloxone injection is an antagonist that will reverse the actions of opiates. This reversal can occur when the opiate drug is being used clinically and when it is being abused. Physically dependent patients may experience withdrawal symptoms. Abrupt postoperative opioid reversal has resulted in hypotension, ventricular tachycardia and fibrillation, pulmonary edema, cardiac arrest, encephalopathy, and death.
MANAGEMENT: Patients receiving naloxone injection should be monitored for changes in vital signs, nausea, vomiting, diarrhea, aches, fever, runny nose, sneezing, nervousness, irritability, shivering, abdominal cramps.
- Cerner Multum, Inc. "Australian Product Information." O 0
- Gilman AG, Rall TW, Nies AS, Taylor P, eds. "Goodman and Gilman's the Pharmacological Basis of Therapeutics. 8th ed." New York, NY: Pergamon Press Inc. (1990):
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Narcan (naloxone)." DuPont Pharmaceuticals, Wilmington, DE.
Generic Name: naloxone
Brand name: Narcan, Evzio
Synonyms: Naloxone (nasal), Naloxone
Generic Name: oxycodone
Brand name: Oxaydo, Roxybond, Oxycontin, Oxyfast, Roxicodone, Xtampza ER, Oxecta, Oxycontin, Xtampza ER; oxycodone is also present in the following combination drugs: Combunox, Endocet, Endodan, Moxduo, Oxycodan, Percocet, Percodan, Primlev, Roxicet, Xartemis XR, and others, OxyIR, Roxybond
Synonyms: RoxyBond (Oxycodone Tablets), Roxybond
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Naloxone Injection-RoxyBond (Oxycodone Tablets)
- Naloxone Injection-Rozerem
- Naloxone Injection-Rozex Topical
- Naloxone Injection-Rozlytrek
- Naloxone Injection-Ru-Hist Forte
- Naloxone Injection-Ru-Hist-D
- Roxybond (Oxycodone Capsules and Tablets)-Naloxone nasal
- Roxybond (Oxycodone Capsules and Tablets)-Naloxone Nasal Spray
- Roxybond (Oxycodone Capsules and Tablets)-Naltrexone
- Roxybond (Oxycodone Capsules and Tablets)-Naltrexone and Bupropion
- Roxybond (Oxycodone Capsules and Tablets)-Naltrexone Hydrochloride And Bupropion Hydrochloride
- Roxybond (Oxycodone Capsules and Tablets)-Naltrexone injection