Naprelan and Vorapaxar Sulfate
Determining the interaction of Naprelan and Vorapaxar Sulfate and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using vorapaxar together with naproxen may increase the risk of bleeding, including severe and sometimes fatal hemorrhage. Talk to your doctor if you have any questions or concerns. Your doctor may already be aware of the risks, but has determined that this is the best course of treatment for you and has taken appropriate precautions and is monitoring you closely for any potential complications. You should seek immediate medical attention if you experience any unusual bleeding or bruising, or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR CLOSELY: Concomitant use of vorapaxar with other agents that affect hemostasis such as anticoagulants, platelet inhibitors, thrombin inhibitors, thrombolytic agents, dextran, nonsteroidal anti-inflammatory agents (chronic), or agents that commonly cause thrombocytopenia may increase the risk of bleeding.
MANAGEMENT: Caution is advised if vorapaxar is used in combination with other drugs that affect hemostasis. Close clinical and laboratory observation for hemorrhagic complications is recommended. Patients should be advised to promptly report any signs of bleeding to their doctor, including pain, swelling, headache, dizziness, weakness, prolonged bleeding from cuts, increased menstrual flow, vaginal bleeding, nosebleeds, bleeding of gums from brushing, unusual bleeding or bruising, red or brown urine, or red or black stools.
- "Product Information. Zontivity (vorapaxar)." Merck & Company Inc, Whitehouse Station, NJ.
Generic Name: naproxen
Brand name: Aleve, EC-Naprosyn, Flanax Pain Reliever, Midol Extended Relief, Naprelan 375, Naprosyn, Anaprox-DS, Naprelan 500, Flanax, Naprelan, Anaprox, Naproxen Sodium, Aleve Caplet, Aleve Gelcap, Aleve Easy Open Arthritis
Synonyms: Naprelan (Oral)
Generic Name: vorapaxar
Brand name: Zontivity
Synonyms: Vorapaxar
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Naprelan-Voraxaze
- Naprelan-Voriconazole
- Naprelan-Voriconazole Injection
- Naprelan-Voriconazole Oral, Intravenous
- Naprelan-Voriconazole oral/injection
- Naprelan-Voriconazole Suspension
- Vorapaxar Sulfate-Naprelan 500
- Vorapaxar Sulfate-Naprelan Dose Card
- Vorapaxar Sulfate-Naprosyn
- Vorapaxar Sulfate-Naprosyn Oral Suspension
- Vorapaxar Sulfate-Naprosyn Tablets
- Vorapaxar Sulfate-Naproxen