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Naproxen and Esomeprazole and Prenatal multivitamins

Determining the interaction of Naproxen and Esomeprazole and Prenatal multivitamins and the possibility of their joint administration.

Check result:
Naproxen and Esomeprazole <> Prenatal multivitamins
Relevance: 11.10.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Talk to your doctor before using naproxen together with esomeprazole. Using these medications together may affect the enteric coating of naproxen, causing the medication to be released too early in the body. This can make naproxen less effective. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: Theoretically, proton pump inhibitors may decrease the gastrointestinal absorption of enteric-coated naproxen, which requires an acidic environment for dissolution. The proposed mechanism is an increase in gastric pH (i.e. decreased gastric acidity) induced by proton pump inhibitors. In patients treated with proton pump inhibitors, the possibility of a reduced or subtherapeutic response to enteric-coated naproxen should be considered.

MANAGEMENT: Concomitant use of these drugs is generally not recommended.

References
  • "Product Information. Naprosyn (naproxen)." Syntex Laboratories Inc, Palo Alto, CA.
Naproxen and Esomeprazole

Generic Name: esomeprazole / naproxen

Brand name: Vimovo

Synonyms: Esomeprazole and naproxen

Prenatal multivitamins

Generic Name: multivitamin, prenatal

Brand name: Vynatal FA, Zenate, CitraNatal Bloom, CitraNatal Bloom DHA, CitraNatal DHA, CitraNatal Harmony, CitraNatal Rx, Concept DHA, Concept OB, Duet DHA Balanced, Femecal OB, Folcaps Care One, Folet DHA, Folet One, Foltabs Prenatal, Foltabs Prenatal Plus DHA, Gesticare DHA, Infanate Balance, KPN Prenatal, M-Natal Plus, Mini-Prenatal, Multi-Nate 30, NeoNatal Plus, NeoNatal Vitamin, Nestabs ABC, Nexa Plus, Niva-Plus, Néevo DHA, OB Complete Gold, OB Complete One, OB Complete Petite, OB Complete Premier, One A Day Women’s Prenatal, OptiNate, Paire OB Plus DHA, PreCare, PreferaOB + DHA, PreferaOB One, PreferaOB, Prena1, Prena1 True, Prenatal 19, Prenatal One Daily, Prenatal Rx 1, Prenate AM, Prenate DHA, Prenate Essential, Prenate Mini, Prenate Pixie, Prenate Star, PreNexa Premier, Provida DHA, TriCare Prenatal, TriCare Prenatal DHA One, TriStart DHA, VIL-Rx, Vinate Care, Virt Nate, Virt-Advance, Virt-C DHA, Virt-PN DHA, Virt-PN, Virt-Vite GT, VirtPrex, Vitafol Ultra, Vitafol-Nano, Vitafol-OB+DHA, VitaPhil + DHA, Vol-Tab Rx, VP-CH-PNV, VP-Heme OB + DHA, VP-Heme OB, VP-PNV-DHA, CitraNatal DHA, PreNata, Choice-OB+DHA, Select-OB+DHA, Stuart One

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.