Naproxen CR Tablets and Ticlopidine
Determining the interaction of Naproxen CR Tablets and Ticlopidine and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using naproxen together with ticlopidine can cause you to bleed more easily. Call your doctor promptly if you have any unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness. You should also avoid any other over-the-counter NSAID products. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Ticlopidine has been reported to potentiate the effect of nonsteroidal anti-inflammatory agents (NSAIDs) on platelet aggregation. The risk of bleeding may be increased, especially in patients with a history of gastrointestinal (GI) ulceration or bleeding. The safety of concomitant use has not been established.
MANAGEMENT: Patients should be monitored for signs and symptoms of bleeding, especially GI bleeding, if NSAIDs and ticlopidine are coadministered. They should be advised to promptly report any signs of bleeding to their physician, including abdominal pain, vomiting blood, red or black stools, swelling, headache, dizziness, weakness, prolonged bleeding from cuts, nosebleeds, bleeding of gums from brushing, red or brown urine, or other unusual bleeding or bruising. Patients should also be counseled to avoid any other over-the-counter NSAID products.
- "Product Information. Ticlid (ticlopidine)." Syntex Laboratories Inc, Palo Alto, CA.
Generic Name: naproxen
Brand name: Aleve, EC-Naprosyn, Flanax Pain Reliever, Midol Extended Relief, Naprelan, Naprosyn, Anaprox, Anaprox-DS, Naproxen Sodium, Aleve Caplet, Aleve Gelcap, Aleve Easy Open Arthritis, Naprelan 375, Naprelan 500, Flanax
Synonyms: Naproxen
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Naproxen CR Tablets-Ticlopidine Hydrochloride
- Naproxen CR Tablets-Ticon
- Naproxen CR Tablets-Ticon oral/injection
- Naproxen CR Tablets-Tigan
- Naproxen CR Tablets-Tigan (Trimethobenzamide Capsules)
- Naproxen CR Tablets-Tigan (Trimethobenzamide Injection Solution)
- Ticlopidine-Naproxen Delayed Release
- Ticlopidine-Naproxen Modified-Release Tablets
- Ticlopidine-Naproxen Sodium
- Ticlopidine-Naproxen Suspension
- Ticlopidine-Naproxen Tablets
- Ticlopidine-Naproxen Tablets and Capsules