Naproxen Sodium and Rilonacept

• Generic Name: naproxen
• Dosage Forms: n.a.
• Other Brand Names: Aleve, EC-Naprosyn, Flanax Pain Reliever, Midol Extended Relief, Naprelan, Naprosyn, Anaprox, Anaprox-DS, Naproxen Sodium, Aleve Caplet, Aleve Gelcap, Aleve Easy Open Arthritis, Naprelan 375, Naprelan 500, Flanax

Consider potential benefits and risks of naproxen therapy as well as alternative therapies before initiating therapy with the drug. Use lowest effective dosage and shortest duration of therapy consistent with the patient’s treatment goals.

Symptomatic treatment of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. May be used in fixed combination with esomeprazole in patients at risk of developing gastric ulcers associated with NSAIA therapy.

Symptomatic treatment of tendinitis, bursitis, and acute gout.

Management of juvenile rheumatoid arthritis in children ≥2 years of age.

Relief of pain.

NSAIAs considered first-line agents for mild to moderate migraine attacks or for severe attacks that have responded in the past to NSAIAs or nonopiate analgesics.

Self-medication in children ≥12 years of age and adults for the temporary relief of minor aches and pain associated with the common cold, headache, toothache, muscular aches, backache, and minor pain of arthritis.

Symptomatic management of primary dysmenorrhea.

Self-medication for the temporary relief of minor aches and pain associated with menstrual cramps.

Self-medication for reduction of fever in children ≥12 years of age and adults.

• Generic Name: rilonacept
• Dosage Forms: n.a.
• Other Brand Names: Arcalyst

Rilonacept is used to treat some of the symptoms of rare genetic conditions such as Familial Cold Auto-inflammatory Syndrome (FCAS) or Muckle-Wells Syndrome (MWS).

FCAS and MWS are inflammatory disorders in which the body develops certain symptoms without a known cause (such as virus, bacteria, or illness). These symptoms include fever, chills, fatigue, and joint pain. More serious symptoms may involve the bones and joints, the central nervous system (deafness, vision loss, mental impairment), or major organs such as the kidneys.

Rilonacept may treat or prevent the symptoms of Familial Cold Auto-inflammatory Syndrome (FCAS) or Muckle-Wells Syndrome (MWS). However, this medication is not a cure for these inherited conditions.

Rilonacept may also be used for purposes not listed in this medication guide.