About us Contacts Drug interactions: 390 212
Drug search by name

Naropin Polyamp and Theo-Dur

Determining the interaction of Naropin Polyamp and Theo-Dur and the possibility of their joint administration.

Check result:
Naropin Polyamp <> Theo-Dur
Relevance: 20.12.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Ropivacaine serum concentrations may increase when given with drugs metabolized by the cytochrome P-450 isoenzyme 1A2. The theorized mechanism is via competitive inhibition. Information is only available from in vitro studies. Theophylline and mexiletine, drugs metabolized by CYP450 1A2, may participate in this interaction.

References
  • "Product Information. Naropin (ropivacaine)." Astra USA, Westborough, MA.
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Naropin Polyamp

Generic Name: ropivacaine

Brand name: Naropin, Naropin Polyamp, Naropin SDV, Naropin Novaplus

Synonyms: n.a.

Theo-Dur

Generic Name: theophylline

Brand name: Elixophyllin, Theo-24, Respbid, T-Phyl, Aerolate III, Slo-Bid Gyrocaps, Slo-Phyllin, Theobid, Theo-Dur, Theolair, Theovent, Bronkodyl, Theo-X, Theo-Time, Theochron, Slo-Phyllin 125, Theoclear LA-130, Aerolate JR, Theolair-SR, Theoclear LA-260, Quibron-T, Quibron-T/SR, Uniphyl, Uni-Dur, Aerolate SR, Slo-Phyllin 80, Theoclear-80, Theo-Dur Sprinkles, Theosol-80, Asmalix, Aquaphyllin, Truxophyllin, Slo-Phyllin 250, TheoCap

Synonyms: Theo-Dur (Oral)

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction