Narvox and Pegloticase Intravenous

• Generic Name: acetaminophen / oxycodone
• Dosage Forms: n.a.
• Other Brand Names: Endocet 10/325, Endocet 25/325, Endocet 5/325, Endocet 75/325, Nalocet, Percocet 10/325, Percocet 25/325, Percocet 5/325, Percocet 75/325, Primalev, Primlev, Roxicet, Xartemis XR, Tylox, Roxilox, Endocet, Percocet 10/650, Percocet 75/500, Perloxx, Magnacet, Narvox, Xolox, Percocet

Oxycodone and acetaminophen combination is used to relieve pain severe enough to require opioid treatment and when other pain medicines did not work well enough or cannot be tolerated.

Acetaminophen is used to relieve pain and reduce fever in patients. It does not become habit-forming when taken for a long time. But acetaminophen may cause other unwanted effects when taken in large doses, including liver damage.

Oxycodone belongs to the group of medicines called narcotic analgesics (pain medicines). It acts on the central nervous system (CNS) to relieve pain.

When oxycodone is used for a long time, it may become habit-forming, causing mental or physical dependence. However, people who have continuing pain should not let the fear of dependence keep them from using narcotics to relieve their pain. Mental dependence (addiction) is not likely to occur when narcotics are used for this purpose. Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly. However, severe withdrawal side effects can usually be prevented by gradually reducing the dose over a period of time before treatment is stopped completely.

This medicine is available only with your doctor's prescription. Percocet® and Xartemis™ are available only under a restricted distribution program called the Opioid Analgesic REMS (Risk Evaluation and Mitigation Strategy) program.

• Generic Name: pegloticase
• Dosage Forms: n.a.
• Other Brand Names: Krystexxa

Pegloticase injection is used to treat chronic gout in adult patients who have already been treated with other medicines that did not work well. Gout is a condition that is caused by too much uric acid in the blood (hyperuricemia).

Pegloticase injection works by causing less uric acid to be produced by the body. Pegloticase will not relieve a gout attack that has already started.

Pegloticase is to be given only by or under the direct supervision of your doctor.