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Navelbine and Retrovir (Zidovudine Syrup)

Determining the interaction of Navelbine and Retrovir (Zidovudine Syrup) and the possibility of their joint administration.

Check result:
Navelbine <> Retrovir (Zidovudine Syrup)
Relevance: 03.10.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Talk to your doctor before using zidovudine together with vinorelbine. Combining these medications may increase the risk of side effects that affect your bone marrow function, resulting in low numbers of different types of blood cells. You may be more likely to develop anemia, bleeding problems, or infections. Contact your doctor if you experience potential signs and symptoms of these conditions such as paleness, fatigue, dizziness, fainting, unusual bleeding or bruising, fever, chills, sore throat, body aches, or other flu-like symptoms. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: The hematologic toxicity associated with zidovudine may be increased by cytotoxic or myelosuppressive agents.

MANAGEMENT: Frequent hematologic monitoring is recommended.

References
  • "Product Information. Retrovir (zidovudine)." Glaxo Wellcome, Research Triangle Park, NC.
Navelbine

Generic Name: vinorelbine

Brand name: Navelbine

Synonyms: Navelbine Injection

Retrovir (Zidovudine Syrup)

Generic Name: zidovudine

Brand name: Retrovir

Synonyms: Retrovir (oral/injection), Retrovir

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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