Nazarin HC and Pegvisomant Subcutaneous

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

HYDROcodone may reduce the effects of pegvisomant. In clinical trials, patients on narcotic medications often required higher blood levels of pegvisomant to achieve adequate treatment response. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: In clinical trials, patients on opioids often required higher serum pegvisomant concentrations to achieve appropriate IGF-I (insulin-like growth factor-I) suppression compared with patients not receiving opioids. The mechanism of interaction is unknown.

MANAGEMENT: Clinicians should be aware of this potential interaction and adjust the dosage of pegvisomant appropriately in patients treated with opioids.

Nazarin HC

Generic Name: guaifenesin / hydrocodone / phenylephrine

Brand name: De-Chlor G, Hydro GP, Nariz HC, Nazarin HC, Simuc-HD, Donatussin DC, Atuss G, Tussafed-HC, Levall 50, Entex HC, Dynatuss HC, Tussafed-HCG, Uni-Lev 50, Crantex HC, Duratuss HD, Gentex HC, Guiaplex HC, Exetuss-HC, Qual-Tussin DC, MonteFlu HC, HydroFed, Mintuss G

Synonyms: n.a.

What is Nazarin HC?

Pegvisomant Subcutaneous

Generic Name: pegvisomant

Brand name: Somavert

Synonyms: Pegvisomant

What is Pegvisomant Subcutaneous?