Nebivolol and valsartan and Neofrin (Phenylephrine Eye Drops 10%)
Determining the interaction of Nebivolol and valsartan and Neofrin (Phenylephrine Eye Drops 10%) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:If you are receiving valsartan and nebivolol together with a medication called an ACE inhibitor, you should talk to your doctor to make sure this treatment is appropriate for your condition. When used in the treatment of heart failure, this three drug combination has been associated with increased side effects and an increased rate of death. The reason for this is not clear. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: In the Valsartan Heart Failure Trial, the combination of valsartan with a beta-blocker and an ACE inhibitor was associated with unfavorable outcomes on morbidity and mortality in heart failure patients. The mechanism is unknown.
MANAGEMENT: The manufacturer recommends that the triple combination of valsartan with a beta-blocker and an ACE inhibitor be avoided in heart failure patients.
- Cerner Multum, Inc. "Australian Product Information." O 0
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Generic Name: nebivolol / valsartan
Brand name: Byvalson
Synonyms: Nebivolol and Valsartan
Generic Name: phenylephrine ophthalmic
Brand name: AK-Dilate, Altafrin, Mydfrin, Neofrin, Relief, Isopto Frin, AK-Nefrin, Neo-Synephrine Ophthalmic, Phenoptic, Prefrin, Ocu-Phrin
Synonyms: Neofrin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Nebivolol and valsartan-Neofrin (Phenylephrine Eye Drops 2.5%)
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- Neofrin (Phenylephrine Eye Drops 10%)-Nebusal
- Neofrin (Phenylephrine Eye Drops 10%)-NebuSal inhalation
- Neofrin (Phenylephrine Eye Drops 10%)-Necitumumab
- Neofrin (Phenylephrine Eye Drops 10%)-Necitumumab Intravenous