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Neoral and Olmesartan Medoxomil, Amlodipine and Hydrochlorothiazide

Determining the interaction of Neoral and Olmesartan Medoxomil, Amlodipine and Hydrochlorothiazide and the possibility of their joint administration.

Check result:

Neoral <> Olmesartan Medoxomil, Amlodipine and Hydrochlorothiazide

Relevance: 28.09.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using cycloSPORINE together with hydroCHLOROthiazide can increase your magnesium and uric acid blood levels. Using these medications together can also damage your kidneys. Symptoms of kidney damage include swelling, weight gain, feeling short of breath, drowsiness, confusion, mood changes, increased thirst, loss of appetite, nausea and vomiting, pain in your lower back, and urinating more or less than usual or not at all. If you take both medications together, tell your doctor if you have any of these symptoms. You may need a dose adjustment or special tests to safely use these medications together. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Coadministration of thiazide or thiazide-like diuretics with cyclosporine may potentially result in hypermagnesemia, hyperuricemia, and increase the risk of nephrotoxicity. The clinical significance is unknown.

MANAGEMENT: Monitoring of renal function, serum electrolytes, uric acid levels, and cyclosporine blood concentrations is advisable during concomitant use. Some authorities advise against concomitant use of these medicines.

References

"Multum Information Services, Inc. Expert Review Panel"
Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Cerner Multum, Inc. "Australian Product Information." O 0

Neoral

Generic Name: cyclosporine

Brand name: Gengraf, Neoral, Sandimmune, Sandimmune

Synonyms: Neoral (Capsules, Modified)

What is Neoral?

Olmesartan Medoxomil, Amlodipine and Hydrochlorothiazide

Generic Name: amlodipine / hydrochlorothiazide / olmesartan

Brand name: Tribenzor

Synonyms: Amlodipine, hydrochlorothiazide, and olmesartan, Olmesartan, Amlodipine, and Hydrochlorothiazide

What is Olmesartan Medoxomil, Amlodipine and Hydrochlorothiazide?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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