Neoral (Cyclosporine Capsules, Modified) and Quinine
Determining the interaction of Neoral (Cyclosporine Capsules, Modified) and Quinine and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:QuiNINE may reduce the blood levels and effects of cycloSPORINE. Contact your doctor if your symptoms worsen or your condition changes during treatment with these medications. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Limited clinical data suggest that the concomitant use of quinine and cyclosporine may reduce blood levels of cyclosporine. The mechanism is unknown. According to a single case report, a patient's cyclosporine levels fell from 328 ng/mL to 107 ng/mL over 7 days after initiation of quinine 600 mg 3 times a day.
MANAGEMENT: Prescribers should be aware of the potential for an interaction.
- Tan HW, Ch'ng SL "Drug interaction between cyclosporine A and quinine in a renal transplant patient with malaria." Singapore Med J 32 (1991): 189-90
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Generic Name: cyclosporine
Brand name: Gengraf, Neoral, Sandimmune, Sandimmune
Synonyms: Neoral (Capsules, Modified), Neoral
Generic Name: quinine
Brand name: Qualaquin, QM-260, Quinamm
Synonyms: QuiNINE
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Neoral (Cyclosporine Capsules, Modified)-Quinine Sulfate
- Neoral (Cyclosporine Capsules, Modified)-Quinine Sulfate Capsules
- Neoral (Cyclosporine Capsules, Modified)-Quinja
- Neoral (Cyclosporine Capsules, Modified)-Quinja Gel
- Neoral (Cyclosporine Capsules, Modified)-Quintabs
- Neoral (Cyclosporine Capsules, Modified)-Quintabs-M
- Quinine-Neoral (Cyclosporine Oral Solution, Modified)
- Quinine-Neoral Oral
- Quinine-Neosar
- Quinine-Neosporin + Pain Relief Ointment
- Quinine-Neosporin AF Topical
- Quinine-Neosporin G.U