Neoral Oral and Zontivity

• Generic Name: cyclosporine
• Dosage Forms: capsule, liquid filled; oral solution
• Other Brand Names: Gengraf, Neoral, Sandimmune, Sandimmune

Cyclosporine is used together with other medicines to prevent the body from rejecting a transplanted organ (eg, kidney, liver, or heart). It belongs to a group of medicines known as immunosuppressive agents.

When a patient receives an organ transplant, the body's white blood cells will try to get rid of (reject) the transplanted organ. Cyclosporine works by suppressing the immune system to prevent the white blood cells from trying to get rid of the transplanted organ.

Cyclosporine is also used to treat severe rheumatoid arthritis in patients who have failed treatment with methotrexate. This medicine is also used to treat adults with severe plaque psoriasis after other treatments (eg, PUVA, retinoids, methotrexate) failed.

Cyclosporine is a very strong medicine. It can cause side effects that can be very serious, such as kidney problems. It may also decrease the body's ability to fight infections. You and your doctor should talk about the benefits of this medicine as well as the risks of using it.

This medicine is available only with your doctor's prescription.

• Generic Name: vorapaxar
• Dosage Forms: tablet, film coated
• Other Brand Names: Zontivity

Zontivity (vorapaxar) helps to prevent platelets in your blood from sticking together and forming a blood clot. An unwanted blood clot can occur with certain heart or blood vessel conditions.

Zontivity is used to lower the risk of stroke or serious heart problems in people who have had a heart attack or a blood vessel disorder affecting circulation in the arms and legs.

Zontivity is sometimes used together with aspirin or clopidogrel (Plavix).