Neratinib Maleate and Paroxetine Hydrochloride

• Generic Name: neratinib
• Dosage Forms: n.a.
• Other Brand Names: Nerlynx

Single-agent therapy for extended adjuvant treatment of HER2-positive, early-stage breast cancer in patients treated with adjuvant trastuzumab therapy. Subgroup analysis suggests a greater effect on invasive disease-free survival in patients with hormone receptor-positive disease, those treated with sequential adjuvant trastuzumab therapy, and those who completed adjuvant trastuzumab therapy within 1 year of randomization.

• Generic Name: paroxetine
• Dosage Forms: n.a.
• Other Brand Names: Brisdelle, Paxil, Paxil CR, Pexeva

Management of major depressive disorder.

Efficacy in hospital settings not established.

Management of OCD; SSRIs reduce but do not completely eliminate obsessions and compulsions.

Management of panic disorder with or without agoraphobia.

Management of social phobia (social anxiety disorder).

Management of generalized anxiety disorder.

Management of PTSD (alone or in combination with psychotherapy).

Management of PMDD.

Has been used for the management of premature ejaculation.

Has been used for the management of diabetic neuropathy.

Has been used for the management of chronic headache.