Nesiritide and Prestalia

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using perindopril and nesiritide together may have additive blood pressure lowering effects. This can cause headaches, dizziness, or feeling like you might pass out. If you take both medications together, tell your doctor if you have any of these symptoms. You may need a dose adjustment or need your blood pressure checked more often if you take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: The coadministration of nesiritide with ACE inhibitors may result in an increase in symptomatic hypotension due to possible additive pharmacodynamic effects in the vasculature. In a clinical trial in which patients were treated with either nesiritide or nitroglycerin therapy, the frequency of symptomatic hypotension was 6% in patients who also received an oral ACE inhibitor, compared to 1% in patients who did not.

MANAGEMENT: Whether used alone or with other agents, nesiritide should be administered only in settings where blood pressure can be closely monitored. The dosage should be reduced or the drug discontinued in patients who develop hypotension.

Nesiritide

Generic Name: nesiritide

Brand name: Natrecor

Synonyms: n.a.

What is Nesiritide?

Prestalia

Generic Name: amlodipine / perindopril

Brand name: Prestalia

Synonyms: n.a.

What is Prestalia?