Nesiritide and Sodium nitroprusside Intravenous
Determining the interaction of Nesiritide and Sodium nitroprusside Intravenous and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using sodium nitroprusside and nesiritide together may have additive blood pressure lowering effects. This can cause headaches, dizziness, or feeling like you might pass out. If you take both medications together, tell your doctor if you have any of these symptoms. You may need a dose adjustment or need your blood pressure checked more often if you take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: The coadministration of nesiritide with intravenous vasodilators such as nitroglycerin, nitroprusside, and milrinone has not been evaluated. Theoretically, an increase in symptomatic hypotension may occur due to possible additive pharmacodynamic effects in the vasculature. A similar risk may exist during coadministration with oral vasodilators such as hydralazine and minoxidil and other agents with vasodilating effects.
MANAGEMENT: Whether used alone or with other agents, nesiritide should be administered only in settings where blood pressure can be closely monitored. The dosage should be reduced or the drug discontinued in patients who develop hypotension.
- "Product Information. Natrecore (nesiritide)" Scios Inc, Sunnyvale, CA.
Generic Name: nitroprusside
Brand name: Nitropress, Nipride RTU
Synonyms: Nitroprusside
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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