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Neut and Rimactane

Determining the interaction of Neut and Rimactane and the possibility of their joint administration.

Check result:

Neut <> Rimactane

Relevance: 20.09.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using sodium bicarbonate together with rifAMPin may decrease the effects of rifAMPin. RifAMPin should be administered at least 1 hour before sodium bicarbonate. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

ADJUST DOSING INTERVAL: Limited data suggest that some antacids may decrease the oral bioavailability of rifampin. The mechanisms include decreased dissolution of rifampin in the presence of increased gastric pH and/or aluminum chelation with rifampin. The clinical significance has not been established.

MANAGEMENT: Rifampin should be administered at least 1 hour before antacids. Monitoring for altered therapeutic effect is advisable.

References

"Product Information. Rifadin (rifampin)." Hoechst Marion-Roussel Inc, Kansas City, MO.

Neut

Generic Name: sodium bicarbonate

Brand name: Neut

Synonyms: Neut Injection

What is Neut?

Rimactane

Generic Name: rifampin

Brand name: Rifadin, Rifadin IV, Rimactane

Synonyms: n.a.

What is Rimactane?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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