Drug search by name

Neut and Velpatasvir and Sofosbuvir Tablets

Determining the interaction of Neut and Velpatasvir and Sofosbuvir Tablets and the possibility of their joint administration.

Check result:

Neut <> Velpatasvir and Sofosbuvir Tablets

Relevance: 20.09.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Antacids may interfere with the absorption of velpatasvir and reduce its effectiveness. Products with antacid effects typically contain aluminum hydroxide, calcium carbonate, magnesium hydroxide, magnesium carbonate, magnesium oxide, magaldrate, sodium bicarbonate, and/or sodium citrate. To prevent or minimize the interaction, antacid-containing preparations should be taken 4 hours before or 4 hours after the velpatasvir dose. Talk to your doctor or pharmacist if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

ADJUST DOSING INTERVAL: Concurrent administration of velpatasvir with drugs that elevate gastric pH such as antacids may reduce its gastrointestinal absorption. Velpatasvir exhibits pH-dependent solubility, with increased solubility at lower pH. Drugs that increase gastric pH are expected to decrease the plasma concentration of velpatasvir.

MANAGEMENT: If an antacid is required, the antacid should be taken 4 hours before or 4 hours after administration of sofosbuvir-velpatasvir. The same precaution may be applicable to other drugs with antacid effects.

References

"Product Information. Epclusa (sofosbuvir-velpatasvir)." Gilead Sciences, Foster City, CA.

Neut

Generic Name: sodium bicarbonate

Brand name: Neut

Synonyms: Neut Injection

What is Neut?

Velpatasvir and Sofosbuvir Tablets

Generic Name: sofosbuvir / velpatasvir

Brand name: Epclusa

Synonyms: Sofosbuvir and velpatasvir, Sofosbuvir and Velpatasvir

What is Velpatasvir and Sofosbuvir Tablets?

+ Add a drug Remove all

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

The list of popular interactions