Nevirapine Extended Release and Tasimelteon
Determining the interaction of Nevirapine Extended Release and Tasimelteon and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Nevirapine may reduce the blood levels of tasimelteon, which may make the medication less effective in some cases. Contact your doctor if your symptoms worsen or your condition changes. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration with inducers of CYP450 1A2 and/or 3A4 may decrease the plasma concentrations of tasimelteon, which is primarily metabolized by these isoenzymes. When tasimelteon was administered after 11 days of treatment with the potent CYP450 inducer rifampin 600 mg/day, tasimelteon systemic exposure (AUC) decreased by approximately 90% compared to tasimelteon administered alone. No data are available for use with other, less potent inducers.
MANAGEMENT: The potential for diminished therapeutic effects of tasimelteon should be considered during coadministration with inducers of CYP450 1A2 and/or 3A4. Alternative treatments may be required if an interaction is suspected.
- "Product Information. Hetlioz (tasimelteon)." Vanda Pharmaceuticals Inc, Rockville, MD.
Generic Name: nevirapine
Brand name: Viramune, Viramune XR
Synonyms: Nevirapine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Nevirapine Extended Release-Tasmar
- Nevirapine Extended Release-Tavalisse
- Nevirapine Extended Release-Tavist Allergy
- Nevirapine Extended Release-Tavist ND
- Nevirapine Extended Release-Tavist Sinus
- Nevirapine Extended Release-Taxol
- Tasimelteon-Nevirapine Extended-Release Tablets
- Tasimelteon-Nevirapine Oral Suspension
- Tasimelteon-Nevirapine Suspension
- Tasimelteon-Nevirapine Tablets
- Tasimelteon-New Day
- Tasimelteon-New Terocin