Nexiclon XR and Stalevo 100
Determining the interaction of Nexiclon XR and Stalevo 100 and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using cloNIDine together with levodopa can decrease the effects of levodopa. Contact your doctor if you experience a worsening of parkinson symptoms or an increase in rigidity and other movements. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Limited data suggest that clonidine may decrease the effectiveness of levodopa and piribedil by an unknown mechanism.
MANAGEMENT: During coadministration, the patient should be monitored for signs of increased rigidity and akinesia.
- Tarsy D, Parkes JD, Mardsen CD "Clonidine in Parkinson disease." Arch Neurol 32 (1975): 134-6
- Shoulson I, Chase TN "Clonidine and the anti-parkinsonian response to L-dopa or piribedil." Neuropharmacology 15 (1976): 25-7
Generic Name: clonidine
Brand name: Catapres, Catapres-TTS, Duraclon, Kapvay, Catapres-TTS-1, Catapres-TTS-2, Catapres-TTS-3
Synonyms: Nexiclon XR (Oral)
Generic Name: carbidopa / entacapone / levodopa
Brand name: Stalevo 100, Stalevo 125, Stalevo 150, Stalevo 200, Stalevo 50, Stalevo 75, Stalevo
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Nexiclon XR-Stalevo 125
- Nexiclon XR-Stalevo 150
- Nexiclon XR-Stalevo 200
- Nexiclon XR-Stalevo 50
- Nexiclon XR-Stalevo 75
- Nexiclon XR-Stamaril
- Stalevo 100-Nexiclon XR Suspension
- Stalevo 100-Nexium
- Stalevo 100-Nexium (Esomeprazole Delayed-Release Capsules)
- Stalevo 100-Nexium (Esomeprazole Powder for Suspension)
- Stalevo 100-Nexium 24HR (Esomeprazole Delayed-Release Capsules)
- Stalevo 100-NexIUM 24HR (Esomeprazole Delayed-Release Tablets)