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Nexterone and Xanax

Determining the interaction of Nexterone and Xanax and the possibility of their joint administration.

Check result:

Nexterone <> Xanax

Relevance: 13.11.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Amiodarone may increase the pharmacologic effect of benzodiazepines by its adrenergic blocking effects. Data are available for diazepam. Management consists of monitoring the patient's mental status during coadministration.

References

Wilson JS, Podrid PJ "Side effects from amiodarone." Am Heart J 121 (1991): 158-71
Nolan PE, Marcus FI, Karol MD, Hoyer GL, Gear K "Effect of phenytoin on the clinical pharmacokinetics of amiodarone." J Clin Pharmacol 30 (1990): 1112-9
"Product Information. Xanax XR (alprazolam)." Pfizer U.S. Pharmaceuticals Group, New York, NY.
Kerin NZ, Aragon E, Faitel K, Frumin H, Rubenfire M "Long-term efficacy and toxicity of high- and low-dose amiodarone regimens." J Clin Pharmacol 29 (1989): 418-23
"Product Information. Niravam (alprazolam)." Schwarz Pharma, Mequon, WI.
"Product Information. Xanax (alprazolam)." Pharmacia and Upjohn, Kalamazoo, MI.

Nexterone

Generic Name: amiodarone

Brand name: Nexterone, Pacerone, Cordarone

Synonyms: n.a.

What is Nexterone?

Xanax

Generic Name: alprazolam

Brand name: Niravam, Xanax, Xanax XR, Alprazolam Intensol

Synonyms: n.a.

What is Xanax?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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