Nicoderm CQ and Varenicline tartrate
Determining the interaction of Nicoderm CQ and Varenicline tartrate and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using nicotine together with varenicline can cause an increase in side effects. Contact your doctor if you experience nausea, headache, vomiting, dizziness, and fatigue. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration of varenicline and nicotine replacement therapy has been associated with increased adverse effects. In one study, a higher incidence of nausea, headache, vomiting, dizziness, dyspepsia, and fatigue was observed for the combination compared to transdermal nicotine replacement therapy alone. Eight of the 22 subjects (36%) treated with the combination prematurely discontinued treatment due to adverse events, compared to 1 of 17 (6%) of subjects treated with nicotine replacement therapy and placebo. Varenicline (1 mg orally twice a day) did not affect the pharmacokinetics of nicotine (21 mg/day transdermally) when coadministered for up to 12 days.
MANAGEMENT: The safety and efficacy of varenicline in combination with other smoking cessation therapies have not been established. Tolerability may be reduced if varenicline is coadministered with nicotine replacement therapy.
- "Product Information. Chantix (varenicline)." Pfizer U.S. Pharmaceuticals Group, New York, NY.
Generic Name: nicotine
Brand name: Habitrol, Nicoderm C-Q, Nicotine System Kit, Commit, Leader Nicotine Polacrilex, Nicorelief, Nicorette, Thrive, Nicoderm CQ, Nicotrol Inhaler, Nicotrol NS
Synonyms: Nicoderm C-Q (transdermal)
Generic Name: varenicline
Brand name: Chantix, Chantix Starter Pack, Chantix Continuing Month
Synonyms: Varenicline
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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